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Bupa Foundation medical research grants awarded

Grants held in 2008

Thorgersen-Ntoumani, C (Birmingham), £83,203; "Step by Step: a feasibility study on the promotion of lunchtime walking to increase physical activity and improve mental well-being in sedentary employees."

Quigley, M (Oxford), £126,435; "A population-based study of the health and developmental consequences of preterm birth."

Singhal, R (University Hospital Birmingham), £150,424; Metabolomics in prediction of response to neoadjuvant chemotherapy in patients with oesophageal adenocarcinoma

Fitzgerald, R (Cambridge University), £216,762; "Development of biomarkers and novel sampling techniques for screening and surveillance of Barrett's Oesophagus."

Lawton, R (University of Leeds), £50,000 (additional to earlier grant of £332,172); "Increasing physical activity: designing and testing a workplace intervention."

Mason, S (Sheffield), £52,732; "What are the safety, quality and training implications of the four-hour target for emergency departments in the UK?"

Burney, P (Imperial College London), £99,138; "Global Burden of Chronic Respiratory Disease."

Oakeshott, P (St Georges University of London), £141,658; "Prevalence and incidence of genital human papillomavirus (HPV) infection in multiethnic, sexually active young women: community based cohort study."

Moorthy (Imperial College London), £170,082; "Improving the quality of care of emergency surgical patients."

Taylor , R (Penisula Medical School), £9,988; "The effect of targeted exercise on falls and function with people with Parkinson's disease (GET uP): an economic evaluation."

Winters,Z (University of Bristol), £179,400; "Differences between hospital death rates following elective repair of abdominal aortic aneurysm (ERA) with allowance for risk factors."

Livingston, G (UCL), £120,819; "The CHOICE study - Choice Optimisation for Carers."

Stack, E (University of Southampton), £88,489; "The prediction, assessment and prevention of falls among people with Parkinson's Disease and cognitive co-morbidity."

Owen, D (St Georges University of London), £11,183 (additional to earlier grant of £98,741); "Retinal microvascular structure in British children of South Asian, African-Caribbean and White European origin."

Garralda, E (Imperial College London), £57,240; "A surveillance study of the incidence, associated factors and short-term outcome of Conversion Disorder in children in United Kingdom and Ireland."

Dawson (Oxford), £142,513; "Prospective assessment of outcomes and satisfaction with foot and ankle surgery, and evaluation of the new MOXFQ patient-reported outcome measure in relation to surgery on different regions of the foot and ankle."

Shah, S (St Georges University of London), £144,161; "An investigation of the quality of primary care for older care home residents using linkage within a primary care database."

Shah, S (London School of Hygiene and Tropical Medicine), £20,109; "The Cataract Surgery Case Mix Study."

Mr P Ahrens, (Royal Free Hospital), £49,110; "Randomised controlled multicentre study of conservative management vs. open reduction and internal fixation of mid-shaft clavicle fractures."

Dr B Wright (Selby & York PCT), £56,042; "Would some genetically vulnerable surgical patients benefit from prophylactic serotonergic reuptake inhibitors to prevent poor postoperative psychological recovery? Phase 1: Serotonin transporter gene polymorphisms as predictors for recovery after laproscopic cholecystectomy."

Professor N Maffuli (Keele University/University North Staffordshire), £7000; "Comparison of Sub-vastus and standard medial parapatellar approach for a total knee replacement: eight year outcomes following a randomised controlled trial" (PILOT)

Tuffrey-Wijne, I (St George's Hospital), £100,580; "Breaking bad news and communicating about illness with people with learning difficulties."

Reilly, J (University of Glasgow), £78,150; "Paradigm shift in use of physical activity in treatment and prevention: associations between objectively measured physical activity and cognition in 11-13 year olds in ALSPAC."

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Grants held in 2007

Dr V Strange, University of London, £266,278 over 30 months. Women’s experiences of childbirth: continuities and discontinuities in social and medical aspects of first childbirth.

Miss A Halliday, St Georges' School of Medicine and Dentistry, £434,335 over a three year period. Asymptomatic Carotid Surgery Trial-2 (ACST-2): An international randomised trial of carotid artery surgery versus stenting in at least 500 patients with asymptomatic carotid artery stenosis.

Dr A Olujohungbe, University Hospital Aintree NHS Trust, £40,000 over two years. A randomised double blind placebo controlled trial of oral Ephedrine and Etilefrine in the prevention of recurrent (stuttering) attacks of priapism in sickle cell disease: A multicentre international study in older children and adults.

Dr J Stephens, University of Wales, Swansea, £96,163 over three years. Incretin hormones, obesity and impaired glucose homeostasis: Bariatric surgery as a tool to study the role of incretin hormones in obesity and associated metabolic dysfunction.

University College, Dr R Chen, £120,710 over an eighteen month period. Incidence, predictors and prognosis of dementia in an older population who are socio- economically deprived but at low levels of depression and cardiovascular risk factors.

Dr A Montgomery, University of Bristol, £55,345 over a one year period. Decision-making among pregnant women who have had a previous caesarean section: a qualitative video interview study.

Dr P Oakeshott, St Georges' Medical and Dental School, a further £29,901. Community based trial of screening for Chlamydia trachomatis to prevent pelvic inflammatory disease.

Dr Winter, Papworth Hospital Cambridge, a further £84,050 for randomised controlled trial of video-assisted Thoraloscopic Cytoreductive Pleurectomy compared to Talc Pleurodesis in patients with suspected or proven mesothelioma.

Dr D Kessler, University of Bristol, a further £58,181 for randomised control trial of internet-based vognitive behavioural psychotherapy for depression.

Dr Kim Thomas, University of Nottingham, a further £23,334 for a randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis (erysipelas) of the leg.

Dr A Davies, University of Wales, Swansea, £43, 697.84 over one year for a research project: "Asymptomatic carriage of cryptosporidium in pre-school age children in the UK."

Professor C Brayne, University of Cambridge, £56,557 over two years for a research project: "Harnessing the potential of prospective population based clinico-pathological studies: harmonisation of datasets and new more powerful analyses."

Dr W Zhang, University of Nottingham, £219,691 over a two year period for a research project: "Nottingham knee osteoarthritis cohort study - risk modification and prevention."

Dr P Edwards, London School of Hygiene and Tropical Medicine, £43,767 over one year for a research project: "Increasing response to postal questionnaires: an updated review of the evidence."

Professor David Strachan, St Georges University of London, £179,506 over three years for a project: "The International Study of Asthma and Allergies in Childhood (ISAAC)."

Mr PO Ahrens, Royal Free Hospital Hampstead NHS Trust, £49,110 over three yearss for a project: "Randomised controlled multicentre study of conservative management vs open reduction and internal fixation of mid-term clavicle fractures."

Mr Patrick Coughlin, Hull Royal Infirmary, £88,537 over two years for a project: "Biomechanical variables that influence performance of daily tasks in patients with lower limb ischaemia."

Professor David Melzer, Peninsula College of Medicine and Dentistry, £116,901 over two yearsfor a project: "Genetic variation and the health of middle-aged and older workers."

Dr Christopher Owen, St Georges University of London, £98,741 over two years for a project: "Retinal microvascular structure in British children of South Asian, African Caribbean and White European origin."

Mr Michael Clarke, Newcastle University, £34,419 over two years for a project: "The improving outcomes in intermittent exotropia study: Developing a patient care pathway."

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Grants held in 2006

The following projects were awarded Bupa Foundation medical research grants in 2006.

Dr J Dale, Warwick Medical School, a further £25,723. Telecare motivational interviewing for Diabetes patient education and support.

Professor Bath, University of Nottingham, a further £49,583. Improving the management of blood pressure in acute stroke: the efficacy of nitric oxide in stroke (ENOS) study.

Professor S Jackson, University of Nottingham, £127,476 over a three year period. Evaluating robot-assisted shaping therapy as an effective means to facilitate upper limb recovery following stroke.

Dr D Bates, Frenchay Hospital Bristol, £74,619 over a three-year period. The prognostic value of the Shield index in melanoma.

Mr M Caputo, University of Bristol, £88,040 over a two-year period. Neurological evaluation and intelligence testing in cyanotic children undergoing open heart surgery using normoxic or hyperoxic cardiopulmonary bypass.

Dr R McNally, University of Newcastle, £182,699 over a three-year period. An epidemiological study of gender-related differences in susceptibility to childhood cancer.

Dr N Siddiqi, University of Leeds, £118,969 over two-year period. A multi-component intervention to prevent delirium and improve its management in nursing and residential homes.

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Grants held in 2005

The following projects were awarded Bupa Foundation medical research grants in 2005.

Professor N Wald Barts and the London, Queen Mary's School of Medicine and Dentistry for £24,363 over one-year period. Randomised trial of helicobacter pylori screening.

Professor S Lovestone Institute of Psychiatry, King's College London for £311,336 over three years. Integrating clinical outcomes and biomarkers in dementia: GSK-3 and quality of life.

Dr J Knight, The Stroke Association for £179,805 over three years. Asymptomatic carotid surgery trial (ACST) - 10-year results.

Dr L Baum, Chinese University of Hong Kong for £12,260 over 15 months. A pilot study of curcumin for treating alzheimer's disease.

Ms J Fleming, University of Cambridge for £159,719 over three years. Living and dying in extreme old age - a qualitative and quantitative study.

Ms C Bamford, University of Newcastle for £200,647 over two years. Improving patient-centred care for people with dementia in medical encounters.

Professor P Salmon, University of Liverpool for £82,148 over 18 months. Patients' perspective on traditional and innovative regimens for hip arthroplasty.

Dr R Kneebone, Imperial College London for £298,398 over three years. Reducing stress in surgeons: developing an interventional tool.

Dr C W McGrother, University of Leicester for £104,120 over two years. Evaluation of diet and lifestyle, co-morbidity and socio-economic factors in urinary storage disorder in women.

Double-blind randomised cross-over trial to assess the value of screening in an adult population for hypothyroidism. Professor M Law, Barts' and The London Queen Mary's School of Medicine and Dentistry for £92,033 over three years.

Dr N Fox, University College London for £58,924 over one year. The diagnostic value and significance of ECG in the detection and monitoring of Alzheimer's disease.

Dr S Langan, University of Nottingham for £127,855 over two years. A prospective study of the effects of environmental factors on atopic eczema in children.

Professor J Konje, University of Leicester for £143,798 over two years. An evaluation of the role of the plasma endocannabinoid, anandamide in the prediction of preterm delivery - an important cause of significant morbidity and disability.

Dr D Phillips, University of Southampton for £34,232 over 18 months. Early physiotherapy for acute Lower Back Pain ("LBP") in health care workers.

Dr K Thomas, University of Nottingham for £191,654 over four years. A randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis (erysipelas) of the leg.

Dr A Miles, University of Bath for 155,392 over three years. The optimisation of the handling and flow characteristics of biomaterials suitable for spinal augmentation procedures.

Professor R Williams, University of Wales Swansea for £67,098 over two years. Examining the effectiveness of peer lead education for type 2 diabetes and cardiovascular disease in UK Bangladeshi population.

Dr K Ballard, University of Surrey for £47,518 over one year. The development and validation of a multi-dimensional, non-surgical measure to diagnose endometriosis and differentiate between superficial and deep disease.

Mr P McCulloch, University of Oxford for £294,181 over two years. Can team communications training improve behaviour, attitudes, error rates or outcomes in the operating theatre?

Professor C Orpwood, Bath Institute of Medical Engineering for £25,609 over two years. Proposal to evaluate autonomous smart home installation for people with dementia.

Professor I Roberts, London School of Hygiene and Tropical Medicine for £219,707 over two years. The CRASH-2 trial (clinical randomisation of an antifibrinolytic in significant haemorrhage).

Professor S Roulstone, University of the West of England for £112,337 over two years. Predicting persistence, resolution and outcomes of stuttering in children in the Avon longitudinal study of parents and children (ALSPAC).

Dr E Murray, Royal Free and University Medical School for ££80,332 over three years. How does an internet intervention help patients with coronary heart disease achieve better health?

Professor C Ballard, Kings College London for £154,794 over three years. The frequency, outcome and causes of post-operative cognitive decline in older people.

Dr M Blanchard, Royal Free and University Hospital Medical School for £214,596 over three years. Palliative care in patients with advanced dementia and their carers: assessment of need and development of an intervention.

Dr K Brain, Cardiff University School of Medicine for £198,015 over three years. A psychological evaluation of familial ovarian cancer screening.

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Bupa Foundation grants held in 2004

The following projects were awarded Bupa Foundation medical research grants in 2004.

Mr J N'Dow, University of Aberdeen £179,857 Prospective collaborative study of patients with intestinal segments transposed into the urinary tract following surgery for bladder cancer or benign end-stage bladder disease.

Dr A McPherson, University of Oxford £98,921 Immunising children: The experiences of parents in decision making and choice.

Professor R Williams, University of Wales, Swansea £152,504 The prevalence and characterisation of latent autoimmune diabetes.

Dr D Kessler University of Bristol £329,504 randomised controlled trial of internet-based cognitive behavioural psychotherapy for depression.

Mr R Illing University of Oxford £9,071 High intensity focused ultrasound in the management of small renal tumours.

Dr J Hamilton-Shield University of Bristol £118,652 Can a novel treatment using mandometer technology improve weight loss in a child obesity clinic?

Dr Beard University of Oxford £44,292 Is minimally invasive total hip replacement clinically advantageous, safe and cost effective compared to conventional total hip arthroplasty.

Dr P Oakeshott St George's Hospital Medical School, London £145,876 Community-based trial of screening for chlamydia trachomatis to prevent pelvic inflammatory disease.

Dr A Barnicoat University College London £12,415 Communicating genetics with learning disabled people.

Dr H Davies Sheffield Children's Hospital NHS Trust £146,563 Harnessing patient expertise to improve patient-doctor communication.

Professor A Pierro, Institute of Child Health and Great Ormond Street Hospital for Children £180,492 Minimal access repair of contralateral hernias (MARCH randomised controlled trial) laproscopic versus open repair of inguinal hernias in infants.

Mr RT Steffen Nuffield Orthopaedic Centre £47,024 The effect of hip resurfacing on blood flow in the femoral head.

Mr P Hall Addensbrookes Hospital, Cambridge £56,801 Diagnosing suspicious pigmented skin lesions in primary care using the SIAscope.

Dr P Rothwell University of Oxford £161,544 Improving the effectiveness of early prevention of stroke after TIA or minor stroke.

Dr L Brabin University of Manchester £153,040 The role of chlamydia for screening young women requesting emergency hormonal contraception (EHC).

Professor P Thomas Dorset Research and Development Support Unit £59,131 Adaptation, development, process evaluation and three centre pilot of a fatigue management programme for multiple sclerosis.

Professor D Henson Manchester University and Manchester Royal Eye Hospital £74,434 Clinical and social risk factors for sight loss in primary open-angle glaucoma.

Dr N Panay and Dr B Cloke Hammersmith Queen Charlotte's and Chelsea Hospital £5720 A randomised double-blind placebo-controlled trial of oral misoprostol for cervical priming before outpatient hysteroscopy.

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Bupa Foundation grants held in 2003

The following projects were awarded Bupa Foundation medical research grants in 2003.

Dr H Prosser, University of Liverpool. The content and perception of prescription drug information in the print news media.

Dr A M Brooke, University of Leicester. Genotype, environment and ethnicity in the natural history of asthma in childhood.

Dr R Winter, Papworth Hospital NHS Trust. Prospective RCT of VATS cytoreductive pleurectomy compared to talk pleurodesis in patients with suspected or proven malignant mesothelioma.

Dr A Metcalfe, University of Birmingham. Meeting the education and information needs of patients about genetic predisposition to cancer.

Dr C Eccleston, University of Bath. Development of a multi-dimensional inventory to measure the impact of adolescent chronic pain on parents.

Professor B McCormack, University of Ulster. Using older people's stories to inform service development.

Mrs C Moore, National Medical Laser Centre, University College London. The behaviour of light in the prostate - implications for photodynamic therapy for prostate cancer.

Dr J Zakrzewska, Bart's & the London Queen Mary's School of Medicine & Dentistry. Decision analysis in trigeminal neuralgia.

Dr E Murray, Royal Free & University College London. Why do patients use interactive health communication applications, and what criteria do they use for assessing the quality of the application?

Dr J Dale, University of Warwick. Telecare motivational interviewing for diabetes patient education and support.

Dr A Pollard, Oxford Vaccine Group, University of Oxford. Parental perceptions concerning children's participation in research into childhood immunisations.

Professor P Bath, University of Nottingham. Improving the management of blood pressure in acute stroke: the efficacy of nitric oxide in stroke (ENOS) study.

Professor N Habib, Imperial College of Science, Technology & Medicine, London. Radio frequency bipolar bloodless liver tumour resection device.

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Bupa Foundation grants held in 2002

Professor N J Wald, Wolfson Institute. Helicobacter Pylori Project.

Dr G Neale, AVMA. Development of a practical method for case record review in hospital practice.

Mr A S Ali-Khan, University of Bristol. The prognostic value and significance of adhesion molecules in melanocytic lesions.

Dr J Powell, University of London. Surgery for subarachnoid haemorrhage: Can post-surgical support from a clinical nurse specialist reduce adverse psychological and functional outcomes?

Professor M Reed, University of Sheffield. Endoscopic ablation of barratts oesophagus (RCT).

Professor N J Wald, Wolfson Institute. Maintenance of blood samples.

Professor C Bradshaw, Marsden Rd Health Centre. A study to examine how quickly patients recover from common surgical procedures.

Dr S Roberts, Oxford University. Development of a brain-computer interfacing system for people with severe disabilities.

Dr S Logan, Institute of Child Health. Can clinical trial results be trusted?

Professor R Reznek, Queen Mary and Westfield College, Medical & Dental School, St Bartholomew's Hospital, London. Magnetic Resonance (MR) Lymphograhy in the pre-operative assessment of gynaecological malignancies: evaluation of a new MR contrast agent.

Dr D M Tappin. University of Glasgow, Smokechange.

Professor A Pierro, University College London/Institute of Child Health. Promoting glutathione synthesis in critically ill septic infants and children.

Dr E Hypponen and Professor C Power, Institute of Child Health, University College London. Vitamin D status in mid-life: a study of disease risk; seasonal and geographical variation in the 1958 cohort.

Professor G D Angelini, Bristol Heart Institute, University of Bristol. Normoxic vs hyperoxic cardiopulmonary bypass in children undergoing repair of Tetralogy of Fallot.

Professor M Marshall, University of Manchester. Informing the public about the quality of health care.

Dr A Ashcroft, Imperial College London. Social exclusion and trust in the use of medical records.

Dr J S Rahi, Institute of Child Health, University College London. An investigation of risk factors for, and outcomes of, ophthalmic disorders in the British 1958 birth cohort.

Mr C Brown, The Royal College of Surgeons of England, London. Self-management for men with uncomplicated lower urinary tract symptoms: A randomised controlled trial against standard therapy.

Professor A Darzi, Imperial College. Development of robotically enhanced operating theatre.

Dr R North, Cardiff University. Evaluation of digital retinal imaging in the detection and quantification of diabetic macular oedema.

Dr T Harris, St George's Hospital Medical School. Longitudinal study of changes in depression, disability, social circumstances and health service use among older people in primary care.

Dr J Dawson, Oxford Brookes University. Validation of an outcomes questionnaire for bunion surgery and exploration of people's pre-surgical expectations of outcome and satisfaction.

Professor R Gray, University of Birmingham, PROSPER: Association of Coloproctology of Great Britain and Ireland. Randomised trial of rectal prolapse surgery.

Professor J R Monson, University of Hull. Virtual versus conventional colonoscopy in the assessment of patients at high risk for colorectal cancer.

Mr R Harrison, The Restoration of Appearance and Function Trust (RAFT), Institute of Plastic Surgery, Mount Vernon Hospital, Middlesex, The elucidation of flexor tendon healing mechanisms and their strategic modification.

Professor P Whincup, St George's Hospital Medical School. Cardiorespiratory consequences of passive smoking in children and adults.

Dr E J Carr, Bournemouth University. Prevalence of patterns of pre-operative anxiety on patients undergoing gynaecological surgery.

Dr V Jenkins, University of Sussex. Exploratory pilot study to investigate whether hormonal therapy for prostate cancer has an adverse effect on cognition.

Dr C Sadler, University of Southampton. A study to determine the influence of life-style, demographic and socio-economic factors on pre-menstrual tension (PMS).

 


Related links

Clinical Research Network
www.crncc.nihr.ac.uk

The Alzheimer's Society
http://alzheimers.org.uk

Bandolier homepage - The Evidence Based Medicine Site, which has received Bupa Foundation funding
www.jr2.ox.ac.uk/bandolier

The Cochrane Library
www.update-software.com/cochrane

The Wellcome Trust research site
www.wellcome.ac.uk

EORTC (European Organisation for research and treatment of cancer)
www.eortc.be

Clinical Trials (tip-limit search to UK)
www.clinicaltrials.gov

Association of Medical Research Charities
www.amrc.org.uk

The James Lind Alliance
www.lindalliance.org

The James Lind Library
www.jameslindlibrary.org

 

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